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KMID : 0362220120390020111
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Journal of The Korean Research Society for Dental Materials
2012 Volume.39 No. 2 p.111 ~ p.118
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Effect of Amine Plasma Polymerization on Osteoblast Attachment of SLA Treated Dental Implant Surface
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Lim Sung-Su
Lee Sang-June
Ko Yeong-Mu
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Abstract
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Sand blast large grit acid etching (SLA) treated titanium (Ti) implant surfaces are known to enhance
osteoblast activity. In this study, SLA treated Ti surface was modified by a low temperature RF discharge
plasma with amine containing monomer such as allylamine (AAm), propylamine (PAAm) and evaluated in
vitro cellular response. The change in wettability and surface morphology of pure Ti surface after the SLA
treatment and plasma treatment were determined using contact angle measurement and field emission
scanning electron microscopy. The chemical bonding state and chemical structure of amine plasma
polymerized SLA/Ti surfaces were examined by Fourier transform infrared techniques and X-ray
photoelectron spectroscopy. The surfaces of pure Ti, SLA treated Ti, and amine plasma polymerized SLA/Ti
surfaces were also examined for their in vitro pre-osteoblast (MC3T3-E1) cells proliferation and
differentiation using MTT assay and ALP activity test. The results of surface characterization showed that
poly allylamine thin films was deposited on SLA/Ti surface after AAm and PAAm plasma treating for 15 min
under a power of 30, 50, and 70W. The changes of surface chemistry and surface topography of Ti by AAm
and PAAm plasma surface modification played main roles in improving the MC3T3-E1 cell proliferation and
differentiation. These results suggest that amine containing polymeric thin films on the SLA treated Ti
surface has an effect on proliferation and differentiation of MC3T3-E1 cells and potential use in
osteo-conductive bone implants.
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KEYWORD
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Titanium implant, SLA treatment, Biocompatibility, Amine containing polymeric thin film
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